Resume as of April 1995

Adrian Glasser, Ph.D. - Consulting Services

Table of Contents

Hartinger Coincidence Refractometer
Focometer
Humphrey Instruments Ultrasound Biomicroscope
Infrared Photorefractometer
The PowerRefractor
Scroll Chuck Tissue Dilator

SERVICES

I am not a clinician. I have no clinical degree (neither O.D. or M.D.), and I have no clinical training. I cannot prescribe medications or corrective lenses or offer medical advice. I have a Ph.D. degree in physiology and have experience in research on accommodation and presbyopia since starting my Ph.D. degree in 1990. I can propose non-invasive optical measurements that can be performed on human subject volunteers and with approval from the University of Houston Human Subjects Committee, I can conduct those investigations of accommodation and presbyopia on volunteer human subjects who have signed approved informed consent forms.

I have performed studies of accommodation and presbyopia on the avian eye, human eye-bank eyes, monkeys, and have undertaken measurements of accommodation in human subjects. I have and do currently serve as a consultant for pharmaceutical companies, legal firms, private individuals, etc. performing research, consulting services, education, and expert opinions. I have given continuing education seminars, invited lectures and scientific reports on the physiological optics and mechanism of accommodation and presbyopia.

I have published scientific papers and book chapters on the mechanism of accommodation, the physiology and optics of accommodation, and the causes of presbyopia.

EQUIPMENT

The following is a partial list of major equipment items that I have available in my research laboratory at the University of Houston. This instrumentation can be used for measuring the optical and physiological accommodative performance of human and/or animal eyes.

Hartinger Coincidence Refractometer: This instrument is used to measure the refractive state of the eye. It is capable of measuring through a 2-1mm pupil. It is possible to measure astigmatism. It is an objective and analogue instrument and therefore requires little patient cooperation and it is accurate. This instrument is no longer manufactured, and this is actually the last new Hartinger purchased from Zeiss.

Focometer: This is a light weight, low cost, no batteries required Badal optometer from InFocus and is used to measure the refractive state of the eye and accommodative amplitude. This instrument has been developed at the University of Houston, College of Optometry and has been kindly loaned to me by InFocus, Inc.

Humphrey Instruments Ultrasound Biomicroscope: This instrument is used clinically to image the anterior segment of the eye. It is a non-invasive procedure. Following topical ocular anesthesia, a scleral cup is placed beneath the eyelids to be examined, filled with goniosol or sterile saline, and the UBM transducer is introduced into this fluid well to allow the eye to be imaged. This provides a real time 2-D image of a 5 mm x 5 mm region of the anterior segment of the eye. Both static images and live video imaging can be obtained. The UBM is no longer manafactured by Humphrey Instruments, and this instrument is the last unit sold by Humphrey Instruments. Paradigm Medical Industries, Inc. now sells this instrument.

Infrared Photorefractometer: This is a custom made device that produces an infrared light source that can be used to observe and measure the accommodative amplitude of human and animal subjects. The infrared light source is mounted in front of an infrared sensitive video camera that captures a live video image of the eye.

Scroll Chuck Tissue Dilator: This is a device for mechanically stretching the anterior segment of an enucleated eye to simulate the optical effects of accommodation on the crystalline lens. This is an improvement over a previous tissue stretching apparatus used by Glasser & Campbell, (1998) to mechanically stretch human eye-bank lenses. The current improvement offers 12 jaws (rather than 8 as in the earlier apparatus). This unit has been designed and built by Chris Kuether of the UHCO TechServices. It is a plastic molded apparatus and the molding process allows many units to be made from the same molds.

The PowerRefractor: This is a fully automated, dynamic, real-time, clinical infrared video based, refractometer. It is capable of measuring refraction and accommodation binocularly at about 25 Hz. It is an excellent tool for both cooperative and uncooperative subjects such as young children. It requires only a 1 meter working distance and provides a dynamically graphed output from which accommodation can be observed directly. This is an excellent instrument for demonstrating dynamic accommodation. The unit is designed by Frank Schaeffel and Stefan Weiss and is available from MultiChannel Systems in Germany. I have no vested interest in this company.

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